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Dr. Raphael Mechoulam

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Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish   

Y. Gaoni, R. Mechoulam  J. Am. Chem. Soc., 1964, 86 (8), pp 1646–1647 DOI: 10.1021/ja01062a046   

http://pubs.acs.org/doi/abs/10.1021/ja01062a046


Isolation and structure of a brain constituent that binds to the cannabinoid receptor WA Devane, L Hanus, A Breuer, RG Pertwee, LA Stevenson, G Griffin, D Gibson, A Mandelbaum, A Etinger, R Mechoulam Science 18 Dec 1992: Vol. 258, Issue 5090, pp. 1946-1949; DOI: 10.1126/science.1470919 

http://science.sciencemag.org/content/258/5090/1946 


Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors, In Biochemical Pharmacology, Volume 50, Issue 1, 1995, Pages 83-90, ISSN 0006-2952 Raphael Mechoulam, Shimon Ben-Shabat, Lumir Hanus, Moshe Ligumsky, Norbert E. Kaminski, Anthony R. Schatz, Asher Gopher, Shlomo Almog, Billy R. Martin, David R. Compton, Roger G. Pertwee, Graeme Griffin, Michael Bayewitch, Jacob Barg, Zvi Vogel https://doi.org/10.1016/0006-2952(95)00109-D.   


2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor  Lumír Hanuš, Saleh Abu-Lafi, Ester Fride, Aviva Breuer, Zvi Vogel, Deborah E. Shalev, Irina Kustanovich, and Raphael Mechoulam doi: 10.1073/pnas.061029898
PNAS March 27, 2001 vol. 98 no. 7 3662-3665   

http://www.pnas.org/content/98/7/3662.abstract


An endogenous cannabinoid (2-AG) is neuroprotective after brain injury 

David Panikashvili, Constantina Simeonidou, Shimon Ben-Shabat, Lumír Hanuš, Aviva Breuer, Raphael Mechoulam & Esther Shohami Nature 413, 527–531 (04 October 2001) doi:10.1038/35097089 https://www.nature.com/articles/35097089   


International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors 

A. C. Howlett, F. Barth, T. I. Bonner, G. Cabral, P. Casellas, W. A. Devane, C. C. Felder, M. Herkenham, K. Mackie, B. R. Martin, R. Mechoulam and R. G. Pertwee Pharmacological Reviews June 2002, 54 (2) 161-202;  http://pharmrev.aspetjournals.org/content/54/2/161.short   


International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2 

R. G. Pertwee, A. C. Howlett, M. E. Abood, S. P. H. Alexander, V. Di Marzo, M. R. Elphick, P. J. Greasley, H. S. Hansen, G. Kunos, K. Mackie, R. Mechoulam and R. A. Ross Pharmacological Reviews December 2010, 62 (4) 588-631; 

DOI: https://doi.org/10.1124/pr.110.003004   


Cannabis and epilepsy 

R. Mechoulam 

DOI: http://dx.doi.org/10.1016/j.yebeh.2017.01.014