Ethan B. Russo MD



1: Russo EB. Cannabis and epilepsy: An ancient treatment returns to the fore.

Epilepsy Behav. 2017 May;70(Pt B):292-297. doi: 10.1016/j.yebeh.2016.09.040. Epub

2016 Dec 15. Review. PubMed PMID: 27989385.

2: Russo EB. Beyond Cannabis: Plants and the Endocannabinoid System. Trends

Pharmacol Sci. 2016 Jul;37(7):594-605. doi: 10.1016/j.tips.2016.04.005. Epub 2016

May 11. Review. PubMed PMID: 27179600.

3: Russo EB. Current Therapeutic Cannabis Controversies and Clinical Trial Design

Issues. Front Pharmacol. 2016 Sep 14;7:309. doi: 10.3389/fphar.2016.00309.

eCollection 2016. Review. PubMed PMID: 27683558; PubMed Central PMCID:


4: Russo EB. Taming THC: potential cannabis synergy and

phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011

Aug;163(7):1344-64. doi: 10.1111/j.1476-5381.2011.01238.x. Review. PubMed PMID:

21749363; PubMed Central PMCID: PMC3165946.

5: Russo EB. Cannabidiol Claims and Misconceptions: (Trends in Pharmacological

Sciences 38, 198-201; 2017). Trends Pharmacol Sci. 2017 May;38(5):499. doi:

10.1016/j.tips.2017.03.006. Epub 2017 Apr 1. PubMed PMID: 28377033.

6: Russo EB. Cannabidiol Claims and Misconceptions. Trends Pharmacol Sci. 2017

Mar;38(3):198-201. doi: 10.1016/j.tips.2016.12.004. Epub 2017 Jan 12. Erratum in:

Trends Pharmacol Sci. 2017 May;38(5):499. PubMed PMID: 28089139.

7: Russo E, Guy GW. A tale of two cannabinoids: the therapeutic rationale for

combining tetrahydrocannabinol and cannabidiol. Med Hypotheses.

2006;66(2):234-46. Epub 2005 Oct 4. PubMed PMID: 16209908.

8: Schoedel KA, Chen N, Hilliard A, White L, Stott C, Russo E, Wright S, Guy G,

Romach MK, Sellers EM. A randomized, double-blind, placebo-controlled, crossover 

study to evaluate the subjective abuse potential and cognitive effects of

nabiximols oromucosal spray in subjects with a history of recreational cannabis

use. Hum Psychopharmacol. 2011 Apr;26(3):224-36. doi: 10.1002/hup.1196. PubMed

PMID: 21671456.

9: Sellers EM, Schoedel K, Bartlett C, Romach M, Russo EB, Stott CG, Wright S,

White L, Duncombe P, Chen CF. A Multiple-Dose, Randomized, Double-Blind,

Placebo-Controlled, Parallel-Group QT/QTc Study to Evaluate the

Electrophysiologic Effects of THC/CBD Spray. Clin Pharmacol Drug Dev. 2013

Jul;2(3):285-94. doi: 10.1002/cpdd.36. Epub 2013 May 14. PubMed PMID: 27121791.

10: Russo EB, Guy GW, Robson PJ. Cannabis, pain, and sleep: lessons from

therapeutic clinical trials of Sativex, a cannabis-based medicine. Chem

Biodivers. 2007 Aug;4(8):1729-43. Review. PubMed PMID: 17712817.

11: Russo EB. Cannabinoids in the management of difficult to treat pain. Ther

Clin Risk Manag. 2008 Feb;4(1):245-59. PubMed PMID: 18728714; PubMed Central

PMCID: PMC2503660.

12: Russo EB. Clinical endocannabinoid deficiency (CECD): can this concept

explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable

bowel syndrome and other treatment-resistant conditions? Neuro Endocrinol Lett.

2004 Feb-Apr;25(1-2):31-9. Review. PubMed PMID: 15159679.

13: Russo EB. Clinical endocannabinoid deficiency (CECD): can this concept

explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable

bowel syndrome and other treatment-resistant conditions? Neuro Endocrinol Lett.

2008 Apr;29(2):192-200. PubMed PMID: 18404144.

14: Russo EB, Jiang HE, Li X, Sutton A, Carboni A, del Bianco F, Mandolino G,

Potter DJ, Zhao YX, Bera S, Zhang YB, Lü EG, Ferguson DK, Hueber F, Zhao LC, Liu 

CJ, Wang YF, Li CS. Phytochemical and genetic analyses of ancient cannabis from

Central Asia. J Exp Bot. 2008;59(15):4171-82. doi: 10.1093/jxb/ern260. PubMed

PMID: 19036842; PubMed Central PMCID: PMC2639026.

15: Russo EB. History of cannabis and its preparations in saga, science, and

sobriquet. Chem Biodivers. 2007 Aug;4(8):1614-48. PubMed PMID: 17712811.

16: Thiagaraj HV, Russo EB, Burnett A, Goldstein E, Thompson CM, Parker KK.

Binding properties of dipropyltryptamine at the human 5-HT1a receptor.

Pharmacology. 2005 Jul;74(4):193-9. Epub 2005 May 9. PubMed PMID: 15886504.

17: Russo EB, Burnett A, Hall B, Parker KK. Agonistic properties of cannabidiol

at 5-HT1a receptors. Neurochem Res. 2005 Aug;30(8):1037-43. PubMed PMID:


18: Weber JT, O'Connor MF, Hayataka K, Colson N, Medora R, Russo EB, Parker KK.

Activity of Parthenolide at 5HT2A receptors. J Nat Prod. 1997 Jun;60(6):651-3.

PubMed PMID: 9214741.

19: Russo E. Cannabis for migraine treatment: the once and future prescription?

An historical and scientific review. Pain. 1998 May;76(1-2):3-8. Review. PubMed

PMID: 9696453.

20: Ryz NR, Remillard DJ, Russo EB. Cannabis Roots: A Traditional Therapy with

Future Potential for Treating Inflammation and Pain. Cannabis Cannabinoid Res.

2017 Aug 1;2(1):210-216. doi: 10.1089/can.2017.0028. eCollection 2017. Review.

PubMed PMID: 29082318; PubMed Central PMCID: PMC5628559.

21: Russo EB, Marcu J. Cannabis Pharmacology: The Usual Suspects and a Few

Promising Leads. Adv Pharmacol. 2017;80:67-134. doi: 10.1016/bs.apha.2017.03.004.

Epub 2017 Jun 5. PubMed PMID: 28826544.

22: Russo EB. Clinical Endocannabinoid Deficiency Reconsidered: Current Research 

Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other

Treatment-Resistant Syndromes. Cannabis Cannabinoid Res. 2016 Jul 1;1(1):154-165.

doi: 10.1089/can.2016.0009. eCollection 2016. Review. PubMed PMID: 28861491;

PubMed Central PMCID: PMC5576607.

23: Piomelli D, Russo EB. The Cannabis sativa Versus Cannabis indica Debate: An

Interview with Ethan Russo, MD. Cannabis Cannabinoid Res. 2016 Jan 1;1(1):44-46. 

doi: 10.1089/can.2015.29003.ebr. eCollection 2016. PubMed PMID: 28861479; PubMed 

Central PMCID: PMC5576603.

24: Russo EB, Merzouki A, Mesa JM, Frey KA, Bach PJ. Cannabis improves night

vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers 

of the Rif mountains of northern Morocco. J Ethnopharmacol. 2004

Jul;93(1):99-104. PubMed PMID: 15182912.

25: Russo EB. Echinacea for the common cold. Ann Intern Med. 2003 Oct

7;139(7):599; author reply 601. PubMed PMID: 14530236.

26: Russo EB. Safety, tolerability, and efficacy of orally administered

cannabinoids in MS. Neurology. 2003 Feb 25;60(4):729-30; author reply 729-30.

PubMed PMID: 12601130.

27: Russo EB, McPartland JM. Cannabis is more than simply

delta(9)-tetrahydrocannabinol. Psychopharmacology (Berl). 2003 Feb;165(4):431-2; 

author reply 433-4. Epub 2002 Dec 19. PubMed PMID: 12491031.

28: Russo EB. Headache treatments by native peoples of the Ecuadorian Amazon: a

preliminary cross-disciplinary assessment. J Ethnopharmacol. 1992

Jun;36(3):193-206. Review. PubMed PMID: 1434677.